Joint pain caused by rheumatoid arthritis can be relieved by non-steroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids, and anti-infective drugs should also be taken to remove the infected foci. 1. Non-steroidal anti-inflammatory drugs: common non-steroidal anti-inflammatory drugs include ibuprofen, etoricoxib, etc. These drugs have anti-inflammatory and analgesic effects, which can effectively eliminate joint inflammation and relieve joint pain symptoms. 2. Glucocorticosteroids: commonly used glucocorticosteroids include methylprednisolone, prednisone, etc. Glucocorticosteroids have strong anti-inflammatory effects, which can effectively relieve joint inflammation in patients. 3. Anti-infective drugs: As rheumatoid arthritis is a reactive arthritis caused by patients infected with group A beta-hemolytic streptococcus, it needs to be treated against this pathogen, and the commonly used drugs are benzylpenicillin, lincomycin, roxithromycin, and cephalosporins. Drugs need to be used under the guidance of a physician, it is recommended that patients with rheumatoid arthritis to the rheumatology and immunology department of the regular hospital for detailed consultation, follow the doctor’s instructions to use drugs.