The difference between papules and eczema is mainly manifested in the causes, symptoms and treatment methods. 1. Etiology: There are more skin diseases that cause pimples, including infectious skin diseases and allergic skin diseases, such as herpes zoster, chickenpox and contact dermatitis, which can lead to the appearance of pimples. The cause of eczema is still unclear, mostly related to genetic factors, immune factors and environmental factors. 2. Symptoms: papules appear as confined elevations above the skin, as small as a pinhead or as large as a soybean, with diverse shapes and purplish-red color; eczema manifests itself as symmetrical erythema, papules and blisters on the skin, which are itchy and painful, and can lead to vesiculation and oozing. 3. Treatment: papules are a kind of skin lesion manifestation, the treatment is mainly for the primary disease, according to the different primary diseases and choose different treatments; local treatment is the main means of eczema treatment, can be used externally with glycerine lotion, hydrocortisone butyrate cream, halomethasone cream and other drug treatment. Pimples and eczema are both dermatologic problems, and it is recommended that a doctor make a clear diagnosis and then target treatment. The above medications should be used in accordance with medical advice.