Vitamin A cream should not be used during pregnancy preparation. Vitamin A cream is mainly used for the treatment of acne and includes both oral and topical preparations. It is recommended to stop taking or topical use of vitamin A cream for 1-3 months before considering pregnancy preparation, which can easily lead to fetal malformation, miscarriage and fetal abortion if used during pregnancy preparation. It is not recommended to use such medication if you are planning to prepare for pregnancy, and if you are using such medication for acne, it is recommended to use contraception when having sex to avoid unwanted pregnancy. It is not recommended that women take or use any drugs topically when preparing for pregnancy or during early pregnancy. If you must use them, it is recommended that you use them under the guidance of a doctor to avoid affecting the development of the fetus in the uterus and affecting the normal development of the fetus, which can cause malformation or miscarriage in serious cases.