Pain in the middle of the chest with gasping for breath and pain on movement may be caused by muscle strain, pleurisy, myocardial ischemia and other factors. 1. Muscle strain: If you have performed strenuous exercise or have not warmed up before exercise, it may lead to muscle strain in the chest, resulting in pain in the middle of the chest and pain when you gasp for breath and move. 2. Pleurisy: If the pleural tissue covering the lungs and chest wall produces an inflammatory reaction, it may lead to the symptoms of pain in the middle of the chest, pain when gasping and moving, which is usually manifested as a sudden stabbing pain that may worsen when breathing, coughing and moving. 3. Myocardial ischemia: If coronary artery stenosis occurs, resulting in insufficient blood supply and oxygen supply to the myocardium, it may cause patients to experience pain in the middle of the chest, gasping for breath and pain when moving, which is usually manifested clinically as angina pectoris, dyspnea, chest tightness and so on. Exercise should pay attention to do a good job of warming up, step by step, if you do not exercise, the symptoms of pain in the middle of the chest, wheezing and pain when you move, you should consult a doctor in a timely manner, so as not to delay the condition.