According to recent literature, the prevalence of diabetes in the Chinese population over 20 years of age is 9.7%, which has reached an epidemic proportion; another 15.5% are in prediabetes. About 0.8% of diabetic patients suffer from diabetic lumbosacral plexus neuropathy; in other words, the prevalence of diabetic lumbosacral plexus neuropathy is nearly 80/100,000, which is no longer a rare disease and deserves the attention of diabetic patients. Diabetic lumbosacral plexus neuropathy is also known as diabetic myasthenia gravis, diabetic proximal neuropathy, diabetic polyneuropathy, and Bruns-Garland syndrome, and the first case was reported by Bruns in 1890. It is mostly seen in patients with type 2 diabetes. Does not correlate with the length or severity of diabetes and is more common in patients with lower body mass index, better glycemic control, lower insulin requirements, and fewer diabetic complications such as retinopathy and heart disease. The clinical manifestations of diabetic lumbosacral radicular plexus neuropathy are highly variable, and the main diagnostic bases are: 1. Symptoms: bilateral asymmetry; proximal prominence; acute or subacute onset; 2. Pain may be present or absent: often the first symptom. Pain in the lower back, unilateral hip anterior thigh: deep sharp and burning pain; 3. Progression to weakness and atrophy of the proximal lower extremity after a few weeks: difficulty in ascending and descending stairs and standing in a seated position, flexion of the lower extremity; 4. Plant neurological disorders: postural hypotension, diaphoresis and sexual dysfunction; Prognosis: recovery is possible, but mostly incomplete and time-consuming. Pain recovers before weakness, and proximal weakness recovers faster and more completely than distal weakness; some patients may have mild to moderate weakness, but it is mostly located in the distal part of the limb; electrophysiological examination: electromyography: abnormal spontaneous potentials in at least two muscles innervated by different peripheral nerves of the lower limb; nerve conduction velocity: decreased cmap of the affected nerve, typically involving the femoral nerve; magnetic resonance, etc. has excluded the corresponding nerve root, nerve The pathogenesis of diabetic lumbosacral nerve root plexus neuropathy has not been finally clarified and may be related to autoimmunity leading to small vascular lesions. Therefore, human gammaglobulin, hormones, and immunosuppressants may be the treatment of choice.