Objective To review and summarize the clinical application of the Double-Switch surgical approach Methods From January 2002 to December 2006, a total of 14 cases were treated with the Double-Switch surgical approach in the surgical correction of complex precordial disease with inconsistent atrioventricular connections. There were 11 male cases and 3 female cases; the age at surgery ranged from 3 months to 7 years, with an average of 39±35.27 months, and the weight ranged from 5 to 31 kg, with an average of 14.23±8.27 kg. There were 9 cases of corrected large-vessel dislocation and 5 cases of right ventricular double outlet with inconsistent atrioventricular connections. The remaining 4 cases without pulmonary stenosis were treated with the Senning + Switch procedure. The remaining 4 cases without pulmonary stenosis were treated by Senning + Switch. The overall surgical mortality rate was 14.28%. There was no complete atrioventricular block in 1 case in the whole group. All surviving cases were followed up from 2 months to 5 years, with one distant death. 9 cases had a 0.2 cm intraventricular residual shunt after the Senning + Rastelli procedure, and 2 cases had an increased superior vena cava return velocity of 1.8 M/S and 2.16 M/S, respectively, with cardiac function in the normal range, and continued follow-up. The results of the four Senning + Switch procedures were satisfactory at follow-up, without any residual shunt or obstruction. The results of the Double-Switch procedure for the treatment of complex precordial disease with inconsistent atrioventricular connections were good, but further follow-up is needed to observe the long-term efficacy of this type of complex surgical approach.