One by one on the calf bone may be due to congenital bone ridge depression, or may be caused by subcutaneous fat grain and other factors. 1. Congenital bone ridge depression: it may be caused by congenital bone ridge depression, most patients’ calf bones are not completely straight, so this symptom may belong to normal physiological factors. 2. Subcutaneous fat grain: due to the phenomenon that the mouth of hair follicles in the calf is occluded, the oil in the hair follicles can not be discharged, there may be fat grain on the calf bone, in addition to hormone level disorders, over-nutrition, and other factors may also appear the phenomenon of fat grain. If the patient has a calf bone touch up a phenomenon, may also be caused by chondroma, varicose veins, cysts and other factors, it is recommended that the patient consult a doctor in a timely manner to clarify the cause of the disease for targeted treatment.