Kidney disease has always been a dreadful disease for people to talk about. Chronic kidney disease not only brings a lot of impacts on one’s health and daily life, but also brings a high economic burden, which is difficult for ordinary families to bear, especially after kidney disease develops into uremia. Kidney disease in China is characterized by “three highs and one low”, the so-called three highs are “high morbidity, high mortality and high medical consumption”. The so-called high morbidity is that the incidence of chronic kidney disease in China is as high as 10.8% of the general population, that is to say, one out of ten people suffers from chronic kidney disease; the high mortality rate refers to the progression of chronic kidney disease patients with the progress of the disease will lead to progressive renal decompensation, and once it develops to the end-stage uremia said that it will be a life-threatening situation and have to accept renal substitution therapy; the high health care consumption is that dialysis of end-stage renal disease patients will need to spend about$10,000 a year for dialysis alone. Patients only dialysis costs about 6 to 100 thousand yuan per year, which is a huge expense for a family. A low refers to the low rate of early diagnosis of kidney disease in China, many people have chronic kidney disease but do not know it, when feeling unwell and then go to the clinic often the condition has developed to a very serious degree. In fact, kidney damage and long-term unhealthy habits and some chronic diseases are closely related, such as hypertension and obesity. Take obesity as an example, a study in China found that about 24.2% of men and 33.9% of women with chronic kidney disease are related to obesity. What are the common clinical diseases that can involve the kidneys? Let’s take a look together! 1, diabetes Diabetes can damage small blood vessels, affecting the filtering function, the blood metabolites can not be metabolized normally, resulting in sodium retention, toxin accumulation. Diabetes can also cause nerve damage, resulting in urine reflux, which in turn causes kidney infection or increased intrarenal pressure. 2.Hypertension Long-term hypertension can lead to blood vessel wall pressure and reduced vascular elasticity. After the renal blood vessels are involved, in turn, it will aggravate hypertension, and a vicious circle occurs. Therefore, hypertensive patients should actively control blood pressure. Lupus is an autoimmune disease that often involves multiple organs and systems, and lupus nephritis occurs when the kidneys are damaged. Lupus nephritis occurs when the kidneys are damaged. It can lead to inflammation and sclerosis of small blood vessels, affecting the filtration function of kidneys. Anorexia nervosa refers to an eating disorder characterized by individuals intentionally causing and maintaining body weight significantly lower than the normal standard (at least 15% lower) by means of dieting, often with malnutrition, metabolic and endocrine disorders. If there is a lack of sodium and water, it can lead to chronic kidney disease, and eventually cause renal failure, especially for those who have binge eating (vomiting, using laxatives). 5.Multiple myeloma Multiple myeloma is a malignant tumor disease of plasma cells. Abnormally proliferating tumor cells mainly infiltrate bone marrow and soft tissues and produce a large number of abnormal monoclonal immunoglobulins, leading to bone destruction, anemia, abnormal immune function and kidney damage. More than half of the patients with multiple myeloma will have kidney injury, the most common manifestation is tubular nephropathy. 6, hemolytic uremic syndrome hemolytic uremic syndrome refers to a group of clinical syndromes with clinical manifestations of microangiopathic hemolytic anemia, thrombocytopenia and acute kidney injury. Damaged red blood cells can obstruct the kidneys and subsequently affect renal function. It usually occurs after 5-10 days of diarrhea and is usually caused by infection, such as E. coli or certain drugs. 7. ANCA vasculitis is a necrotizing vasculitis in which autoantibodies – anti-neutrophil cytoplasmic antibodies – attack small blood vessels in the kidneys and other organs. It can lead to hematuria and proteinuria, as well as renal failure. Patients may show fever, joint muscle pain, strong tea-like urine. 8, urinary tract obstruction If the urine can not be discharged normally, it may retrograde damage to the kidneys, resulting in kidney infection. Common causes include enlarged prostate, prostate cancer, kidney stones, bladder cancer and colon cancer. 9. Thrombosis Thrombotic thrombocytopenic purpura is often associated with kidney damage and can lead to micro-thrombosis, as well as involvement of the brain and heart. Common symptoms include fever, nosebleeds or bleeding gums, diarrhea, chest pain, mental changes, headache, petechiae, and malaise. 10, scleroderma Scleroderma is a rare disease characterized by degeneration, thickening and fibrosis of the skin and connective tissues leading to sclerosis and atrophy, which can cause multi-system damage. Kidney involvement may result in proteinuria and a sudden rise in blood pressure, leading to renal failure.