Cholesterol binds to HDL, which removes cholesterol from the peripheral blood vessels and transports it back to the liver for reuse, making HDL cholesterol the “good cholesterol” and a protective factor against coronary heart disease. A mild increase in LDL cholesterol indicates that the body’s ability to remove cholesterol from the blood is good and is beneficial to the body. However, when it is too high, it can be harmful to the body. The causes may be related to the following factors: 1. Familial hyperlipoproteinemia is congenital and must be systematically examined and treated in a hospital to actively treat the primary disease. 2. It may be related to physical overdose, the use of hormones, insulin, contraceptives, heparin and other drugs, which are not to be worried and can be restored to normal after stopping or reducing the medication. 3.Related to liver lesions. For example, liver cirrhosis, chronic hepatitis, liver damage caused by alcoholism, fatty liver and other diseases may lead to high HDL cholesterol. Therefore, when this indicator is high, the first thing to do is to exclude pathological changes in the liver. A mild increase in HDL cholesterol is good for the body and there is no need to worry about it; when the indicator is too high, we should be alert to primary hyperlipoproteinemia and pathological changes in the liver, and it is recommended to consult a doctor for systematic examination and then treat the symptoms.