The severity of liver injury is based on the indexes of alanine aminotransferase (AST), glutamine aminotransferase (GAT) and bilirubin, and should be combined with relevant auxiliary examinations and the patient’s symptoms and signs. 1. Albumin transaminase and glutamine transaminase: they are more commonly used indicators to assess the severity of liver injury. In liver cells, glutamine transaminase mainly exists in non-mitochondria, while most of the glutamine transaminase exists in mitochondria, and glutamine transaminase and glutamine transaminase are non-characterized intracellular functional enzymes. When hepatocyte injury increases the permeability of the cell membrane, the cytoplasmic glutamine aminotransferase and glutamine aminotransferase are released into the blood, resulting in elevation, such as acute and chronic hepatitis, alcoholic liver disease, cirrhosis and so on. 2. Bilirubin: bilirubin mainly enters into the intestinal tract through the liver, forming a hepatic-intestinal cycle, such as inside and outside the liver in the biliary group, such as cholelithiasis, etc., can lead to the obstruction of bile excretion leading to increased bile loss. In addition, hepatocellular injury, such as viral hepatitis, drug or alcoholic hepatitis can appear elevated bilirubin. In case of liver injury, it is recommended to consult a hospital promptly and follow the doctor’s instructions.