The convex palate is the clinical manifestation of the cranial bone lesion in Marfan syndrome. It is inherited in an autosomal dominant fashion, and the specific pathological mechanisms of the disease are described below. Marfon syndrome is also known as congenital mesodermal dysplasia, Marchesani syndrome, spider’s finger syndrome, and limb elongation. Marfan syndrome is a genetic disorder with a basic defect in connective tissue, often chromosomally dominant. The lesions mainly involve the mesodermal heart, bones, muscles, ligaments and connective tissues. The main clinical manifestations are generalized tubular bone elongation, spider-like fingers (toes) (skeletal lesions); dislocation of the lens of the eye (ocular lesions); joint laxity; macrovascular changes in the heart, dilatation of the root of the ascending aorta, or acute and chronic aortic coarctation, aortic regurgitation or mitral valve prolapse (cardiovascular lesions), and a group of pulmonary and neurological malformations. In many tissues of the body such as endocardium, heart valves, large blood vessels, and bones, there is accumulation of mucopolysaccharides such as chondroitin sulfate A or C, which affects the structure and function of elastic and other connective tissue fibers, resulting in poor development and functional abnormalities in the corresponding organs.