Loss of gallbladder function is mainly judged from clinical manifestations and imaging manifestations, clinical manifestations are mostly seen in loss of appetite, abdominal distension, diarrhea, etc., and imaging manifestations are mostly atrophy of gallbladder, thickening of gallbladder wall. 1. Clinical manifestations: After the loss of gallbladder function, the gallbladder loses the function of storing, concentrating and excreting bile, and the patients may show loss of appetite, nausea, vomiting, abdominal distension, etc. Especially after eating greasy food, due to the lack of bile that assists in the digestion and absorption of fats, so the patients will have steatorrhea. Some of them may be accompanied by symptoms such as pain sensation in the right upper abdomen. 2. Imaging manifestations: The common clinical diseases with loss of gallbladder function are atrophic cholecystitis, etc. A slightly strong echogenic area can be seen in the gallbladder area, and there is no liquid dark area inside the gallbladder. In severe cases, only a strong echogenic mass or striated echoes can be seen. There are other manifestations of gallbladder loss of function, it is recommended to consult a doctor in time, further improve the examination, to clarify the cause of the disease, the professional physician to give appropriate treatment for the cause of the disease.