If you have hepatitis B and have chest discomfort, you should check your liver, heart, lungs and stomach. 1. Liver: some patients with hepatitis B may have swelling and pain in the right upper abdomen, which may involve the chest in severe cases, and they should go to the department of infectious diseases of the hospital for further examination of liver function, liver ultrasound, quantitative DNA of hepatitis B virus, and so on. 2. Heart: cardiac lesions are typically characterized by chest pain and discomfort, ECG, cardiac ultrasound and other related examinations should be performed. 3. Lung: besides coughing up phlegm, lung lesions may also have symptoms such as chest tightness and shortness of breath, chest X-ray or chest CT can be used to make a clear diagnosis. 4. Stomach: when stomach distension occurs due to stomach lesions, it can push up the diaphragm and cause discomfort in the chest, and the cause can be determined by electronic gastroscopy. Hepatitis B patients have many reasons for chest discomfort, not necessarily only caused by hepatitis B, it is recommended to go to the hospital specialist, the specialist doctor’s initial judgment of the condition, and then conduct the necessary auxiliary examination to identify the cause of the disease.