What causes the swelling sensation in the hand needs to be differentiated. If the swelling sensation occurs in one hand, it may be caused by trauma or a blood clot in the upper limb, or inflammation, insect bites, allergies, which can help in differential diagnosis based on the history and clinical manifestations. If both hands are swollen, the local causes are trauma and allergy, while the systemic causes, for women, may be edema during menstruation, or after the application of cosmetics, or after exposure to certain drugs or poisons appear systemic allergies in the hand manifestations. Pathological manifestations are mainly due to heart disease, kidney disease and rheumatic disease, different diseases have their own different characteristics, for example, rheumatoid arthritis, a common rheumatic disease, in addition to swelling of the hands, there may also be stiffness of the fingers, which can be significantly relieved after activities.