1. Can people with epilepsy have children? Most people with epilepsy can work and study normally during the interictal period, and can also get married and have children normally, and take appropriate measures before and after pregnancy to ensure the safety of mother and child. If a female patient still has intractable seizures that are difficult to treat, it is best not to conceive or have children for the time being. The risk of malformation in the offspring of male patients with epilepsy is significantly lower than that of female patients. 2. What are the effects of pregnancy on the fetus in women with epilepsy? There are two main factors that affect the fetus: the seizures themselves, especially the “grand mal” seizures, may cause fetal hypoxia or developmental abnormalities. The risk of various malformations in babies born to women taking antiepileptic drugs is 2-3 times higher (4-8%) than in the normal population. The effects of various antiepileptic drugs on the fetus vary, and it is generally accepted that traditional drugs such as sodium phenytoin, phenobarbital, sodium valproate and carbamazepine have a high teratogenic rate. In addition, fetal malformation is also related to the type and dose of drugs taken by the mother during pregnancy, the more types of drugs taken and the higher the dose, the higher the risk. What should women with epilepsy pay attention to during pregnancy? In taking antiepileptic drugs, female patients should be guided by an epilepsy specialist to plan their family. The seizures should be controlled to a minimum in the first six months of pregnancy, and the medication should be reduced from multiple doses to a single dose as much as possible, maintaining a lower dose that can control seizures, taking medication regularly, and avoiding missed doses or discontinuing medication. Regular prenatal checkups, including obstetrical and gynecological ultrasound, blood level measurement, etc. If necessary, take folic acid and multivitamins routinely to prevent teratogenic effects of medications or possible bleeding tendencies during delivery. When possible, folic acid tablets can be taken from 3 months before to 3 months after pregnancy in slightly larger doses than in women with normal pregnancies, with a supplemental dose range of 0.4-4 mg, depending on the risk factors carried by the patient. If the above preparations are made, 90% of women with epilepsy can have a normal pregnancy and delivery.