Indistinguishability between right and left is a manifestation of Gutzman’s syndrome, which is seen as cortical damage in the parietal angular gyrus of the dominant hemisphere and can be seen clinically in cerebral infarction as well as in cerebral hemorrhage. Also, intracranial occupational disease can cause damage to the cortex of the parietal angular gyrus of the dominant hemisphere. Patients may present with an inability to count, recognize fingers, as well as a lack of left-right distinction, and in some cases, an inability to write. The cause of Gutzman’s syndrome can be determined by CT or MRI of the head, and the patient should be treated for the cause. If it is caused by ischemic cerebrovascular disease, the patient should be given medication to improve circulation and activate blood circulation. If the disease is caused by intracranial occupational disease, the patient should be treated surgically if necessary. In the case of cerebral hemorrhage, conservative or surgical treatment should be given according to the amount of bleeding, and after active treatment, the patient’s symptoms can be reduced.