Girls’ skin is rough and grainy, which may be caused by peripheral keratosis, eczema, dry syndrome and so on. 1. Perichondrial keratosis: it is a common clinical condition caused by genetic factors such as hyperkeratosis of the skin, mainly manifested in different degrees of skin follicles with small particles, and when touched, it can be clearly felt that the skin is rough with a granular sensation, which occurs in the upper arms and thighs and other parts of the body. 2. Eczema: when various factors trigger the weakening of the skin barrier function, the skin is prone to inflammation, fibrous tissue proliferation can appear after the skin roughness particles. 3. Dry syndrome: because of immunity and other factors lead to skin dehydration, epidermal shedding, so the skin is rough. The phenomenon of girls’ skin roughness and granularity, please go to the hospital in time to check and clarify the cause of the disease for targeted treatment.