Nine-valent vaccine generally refers to the nine-valent HPV vaccine, if one has symptoms of high fever after vaccination, one can deal with it through physical cooling, oral medication (such as ibuprofen, etc.) as prescribed by the doctor, and if necessary, consult a doctor in time. Nine-valent HPV vaccine is a biological agent to help women prevent cervical cancer, although the safety and effectiveness of the vaccine is relatively high, but does not rule out that some women will have adverse reactions after vaccination, and fever is one of the more common. If you have a fever after receiving the vaccine, as long as the temperature does not exceed 38.5 degrees, you can handle it by yourself through physical cooling and drinking plenty of water; if the temperature exceeds 38.5, you can follow the doctor’s instructions to take oral antipyretic medication for symptomatic treatment, such as ibuprofen; however, if the temperature is abnormal, accompanied by rashes, diarrhea, and other symptoms, you need to seek medical attention in time to comply with the doctor’s instructions for diagnosis and treatment. Whether you receive the HPV vaccine or other vaccines, fever itself is a relatively common adverse reaction, but how to deal with the specific needs to be based on the degree of fever and the actual condition of the body to make a judgment. After receiving the HPV vaccine, women should pay attention to nursing care, closely observe the changes in the body, and consult their physicians in case of abnormalities.