Contraindications during leukemia chemotherapy are mainly dietary contraindications, activity contraindications, action contraindications and other aspects. 1. Dietary contraindications: prohibit spicy, greasy food, eat light, high protein, high calorie, high fiber food. 2. Activity contraindication: prohibit a lot of activities, should reduce the activities, pay more attention to rest. 3. Action contraindication: it is forbidden to go out, infection and other problems are easy to occur during the period of myelosuppression, it is necessary to reduce the contact with the outside world, reduce unnecessary visits to avoid the occurrence of cross-infection. 4. Other aspects: prohibit the use of hard objects to dig ears, picking tartar and other behaviors, to avoid local injuries leading to skin breakage, soft tissue damage, infection and other complications. There may be other contraindications during chemotherapy for leukemia, which should be implemented in accordance with the doctor’s instructions.