There are many medications that can cause laryngeal oedema, and in some patients the condition is severe, with the severity depending on the dosage and type of medication and the individual’s constitution. Medications include penicillin and sulfadiazine. In addition to laryngeal oedema, patients may experience general malaise, fever, urticaria, skin flushing, angioedema, laryngeal oedema and asthma. Once this set of abnormalities occurs, prompt medical attention is required.