50-year-old woman menopause, coitus pain may be a symptom caused by postmenopause, may also be caused by certain diseases, such as trichomonas vaginitis, vulvovaginal pseudomyxoma, endometrial cancer, etc., should be timely consultation, identify the cause of the disease, and give a combination of estrogen ointment, metronidazole, clotrimazole and other drug therapy or surgical treatment. 1. Symptoms of menopause: Due to the decrease of hormone level after menopause, the vaginal mucosa becomes thin, dry and less elastic, which makes it easy to cause damage to the mucosa during coitus, and thus the symptoms of pain appear. It is suggested that patients should apply the combination of estrogen ointment and other medications under the guidance of the doctor. 2. Vaginitis: Post-menopausal women who suffer from trichomoniasis, vulvovaginal pseudomycosis, which causes vaginal mucosal congestion, can be accompanied by pain during intercourse, and at the same time there is an increase in vaginal discharge, vulvar itching, burning and other symptoms. It is suggested that patients should apply metronidazole, clotrimazole and other medicines under doctor’s instruction. 3. Endometrial cancer: endometrial cancer is a malignant tumor that occurs in the endometrium of the uterus, mostly seen in perimenopausal and postmenopausal women. Patients often take vaginal bleeding and abnormal vaginal discharge as the main clinical manifestations, and when the tumor involves the endocervix, lower abdominal distension and pain in coitus may occur. Surgical treatment is needed, together with postoperative radiotherapy. In addition, cervicitis, pelvic inflammatory disease and other diseases may also lead to the symptoms of pain in coitus after menopause, but this symptom alone is not enough to diagnose the disease, and it should be consulted in time to find out the cause of the disease and be treated accordingly by doctors.