The anti-inflammatory effect is not obvious when the patient takes Pudilan anti-inflammatory tablets for toothache. Pudilan anti-inflammatory tablets are mainly for viral infection, while most of the toothache is caused by bacterial infection, therefore, antibiotic treatment is needed for toothache, including cephalosporin, amoxicillin and erythromycin enteric capsules, and also with the anti-anaerobic bacterial infection treatment drug metronidazole tablets for combined anti-inflammatory treatment, so that the effect will be better. In addition, most people have toothache due to deep caries, pulpitis, or periapical lesions. For patients with toothache, besides using medication, they also need to go to the hospital for dental treatment in order to solve the root of the pain problem. In case of deep caries, resin filling treatment for deep caries will be performed. If the tooth is suffering from pulpitis or periapical inflammation, the tooth will undergo root canal treatment. If the tooth is swollen and painful due to periapical inflammation, an adequate amount of antibiotics should be used to reduce the inflammation, and local rinsing and medication should be applied to the periapical area of the wisdom tooth.