Toothache can be treated with metronidazole tablets. Most toothaches are caused by infections, and metronidazole tablets are commonly used as an anti-anaerobic bacterial infection, and therefore can be used to treat toothache. However, toothache is usually caused by a mixture of aerobic and anaerobic bacteria, so simply taking metronidazole tablets is not enough, and it needs to be combined with broad-spectrum anti-inflammatory drugs such as cephalosporin, erythromycin or amoxicillin to achieve good results. In the acute stage of tooth pain, if the pain is unbearable, you can take painkillers such as ibuprofen and fenpropathrin to relieve the pain. At the same time, you should seek medical attention to check out the specific dental disorder and then treat it symptomatically in order to solve the tooth pain problem at root. Toothache caused by pulpitis and periapical infection requires root canal treatment, while toothache caused by periodontitis requires ultrasonic scaling and periodontal scaling.