Toothache can cause inflammation and enlargement of the lymph nodes, for example, during acute pulpitis, acute attacks of chronic pulpitis, and toothache caused by chronic periapical abscesses can cause inflammation of the lymph nodes. If the nerve inflammation is not controlled in time, the inflammation will progress to the periapical area, forming an abscess, and in severe cases, an interstitial infection will occur causing inflammation and enlargement of the lymph nodes. In patients with periapical wisdom teeth, food residues in the periodontal pockets are not cleaned in time to cause inflammation, which can cause swelling and pus in the jaw and face in severe cases, and can also cause inflammation of the lymph nodes. Routine symptomatic treatment, together with timely anti-inflammatory treatment, is needed to completely solve the problem of inflammation bringing about swollen and inflamed lymph nodes.