It is best to avoid the third vaccine (HPV vaccine, Hepatitis B vaccine, etc.) during menstruation. There may be discomfort during menstruation, for which it is not possible to distinguish whether the discomfort is caused by menstruation or a side effect of the vaccine injection, so it is best to avoid injections during menstruation. The third vaccination, whether it is the new crown vaccine, HPV vaccine, Hepatitis B vaccine, etc., it is best to go to the injection at the specified time, but try to avoid during menstruation, delayed for about a week does not affect the immune effect. After vaccination, the adverse reactions at the site of vaccination are mostly mild, and will usually resolve naturally without special treatment. Systemic adverse reactions are generally mild and self-limiting, and do not require special treatment. Once there are abnormalities after vaccination, you need to go to the hospital in time for a clear diagnosis and standardized treatment under the guidance of the doctor.