1. Are children born after the procedure the same as normal children? According to domestic and international reports, in the case where there is no obvious genetic disease in the preoperative examination of both men and women, there is no statistically significant difference between children born by this technique and other IVF. For cases where genetic diseases exist in both the male and female partners, it is often necessary to decide whether or not to proceed with the procedure after counseling by a geneticist and with the informed consent of both husband and wife. 2.Does testicular micro sperm extraction have any effect on future sex life? The androgen level of these patients is generally low, even without surgery, hormone therapy is needed; in addition, literature reports and our own clinical practice, no obvious adverse effects have been found, and foreign reports that one year after the operation, the androgen level of the patient can be restored to the preoperative level. 3.What is the success rate of sperm extraction and fertilization rate? At present, our hospital has carried out testicular microsperm extraction earlier in Hubei Province, and we have done about 200 cases in the past three years, with the success rate of sperm extraction of 42.68% and the clinical pregnancy rate of 52.88%. 4.What is the operation procedure of testicular micro sperm extraction? (1) Both husband and wife will complete all the examination results of the male partner in the male clinic with fully informed consent; (2) Generally, hospitalization will be 4-5 days, and the sperm will be given to the sperm bank for freezing and preservation after retrieval; if the sperm is not retrieved, the sperm donor may need to be considered for preparation in the future. Nowadays, testicular microsperm retrieval is much more sophisticated and requires much less sperm in terms of quantity and quality. Theoretically, only one morphologically normal, live sperm needs to be obtained, and combined with intracytoplasmic monosperm microinjection, fertilization and pregnancy may be possible, bringing hope for such patients to have offspring; if more sperm can be obtained during the procedure, sparse sperm can be cryopreserved for reuse in the next cycle after the first cycle of treatment fails; if no sperm is obtained during the procedure, or the sperm that is obtained does not meet the requirements of assisted If no sperm is retrieved during surgery, or if the sperm retrieved does not meet the requirements for assisted reproduction therapy, sperm from a human sperm bank can also be used as a “guaranteed solution”.