Calcified nodules in the lungs are usually caused by previous tuberculosis or pneumonia, and clinically old tuberculosis is the most common. If the above imaging changes occur, regular review is clinically recommended to observe any dynamic changes. The nodules in the lungs can be treated next according to morphology, size, and clinical symptoms. If the patient has a small nodule with smooth margins, it is clinically considered a benign nodule and only requires periodic review. If the patient’s nodules are larger, with unsmooth margins and burr signs, malignant nodules are not excluded. Further improvement of tumor series, sputum examination for cancer cells, bronchoscopy, and puncture biopsy of nodules are needed to clarify the diagnosis, and surgery, radiotherapy, chemotherapy, or target cell drug therapy need to be considered after the diagnosis of malignant nodules is confirmed.