Wake up in the morning a lot of yellow snot, according to the causes of yellow snot, targeted choice of antibiotics or other drugs. 1. Sinusitis caused by: adequate use of penicillin antibiotics, such as allergy to penicillin, can be changed to macrolide antibiotics or fluoroquinolone drugs 2. Nasal tumors or nasal polyps: yellow nasal mucus is often seen when nasal tumors or nasal polyps are accompanied by infections, surgery can be performed to remove the tumors or polyps as appropriate, and anti-infective treatment can be actively carried out. 3. Those caused by colds: colds are mostly caused by viral infections, secondary bacterial infections manifested as clear water nasal mucus and then turn into yellow nasal mucus, you can choose Phenmetrazine, Aminophenol Flavonamins and other drugs and anti-infective treatments such as Cephalosporin or Amoxicillin Clavulanate Potassium. Medications should be used under the guidance of a doctor. Caused by yellow nasal discharge may also have other reasons, when there is a persistent yellow nasal discharge symptoms, to the hospital to clarify the cause of the disease in the standardization of targeted treatment.