Hepatitis B patients with total bilirubin value of 42, suggesting the presence of liver function abnormalities, need to be under the guidance of the doctor for standardized treatment. The level of total bilirubin is an important indicator of the degree of liver cell damage, but also an important reason for determining whether the biliary tract is abnormal, and the normal value for adults is 3.4-17.1 umol/L. The sum of direct bilirubin and indirect bilirubin is called total bilirubin. The sum of direct and indirect bilirubin is called total bilirubin. High direct bilirubin indicates that the liver is unable to remove bilirubin properly, and high indirect bilirubin indicates that there are other problems, the specific causes of which are mainly: gallstones, Gilbert’s syndrome (hereditary hyperbilirubinemia), liver function abnormalities, hepatitis, inflammation of the bile ducts, intrahepatic cholestasis in pregnancy, hemolytic anemia, and so on. In any case of abnormal bilirubin, it is necessary to analyze the results of other laboratory tests and to give medication strictly in accordance with the doctor’s instructions.