In some patients with gallbladder stones, due to repeated attacks of gallbladder inflammation, the wall of the gallbladder gradually develops inflammatory hyperplasia and fibrosis, and later slowly forms scars. With such repeated attacks, the gallbladder gradually atrophies and even clings to the gallstones, completely losing the function of contraction and concentration of bile. This condition is medically known as “atrophic cholecystitis”, also known as “sclerosing atrophic crumpled gallbladder”. It is actually the result of a long-term attack of chronic calculous cholecystitis, a special type of calculous cholecystitis. After atrophy, the wall of the gallbladder thickens from the normal 1 to 2 mm to 5-6 mm, or even up to 1 cm. The gallbladder loses its elasticity and becomes hard and small, in some cases less than half its original size. The gallbladder loses its original pale blue, thin, cystic form, and it is tightly adhered to the bile duct, duodenum or part of the stones, with a pile of stones tightly wrapped inside. Ultrasound examination of the gallbladder is mostly unremarkable. The atrophied gallbladder not only loses its physiological function of storing and concentrating bile, but also may develop some other lesions. In addition to occasional symptoms such as right upper abdominal pain, abdominal distension and belching, the stones inside the atrophic gallbladder may also cause jaundice by compressing the adjacent common bile duct, which is called “obstructive jaundice”. Atrophic cholecystitis has a high probability of cancer complications, which is 12-60 times higher than those with normal gallbladder function. Medication for atrophic cholecystitis is hardly effective, and laparoscopic cholecystectomy for lithotripsy is of little significance. Therefore, gallbladder atrophy is unanimously considered by all hepatobiliary surgeons as an indication for cholecystectomy, i.e., cholecystectomy should be performed. However, this surgery is more difficult and the slightest carelessness is very likely to cause damage to the nearby bile ducts or bile ducts. Therefore, when the examination reveals that the gallbladder has atrophied, it is advisable to choose a hospital with better conditions and ask an experienced surgeon to operate in order to avoid regrettable consequences.