Infection after skin flap transplantation should be treated as follows: 1, wound drainage at the first time to drain the fluid and exudate in the wound; 2, bacterial culture of the exudate drained out; 3, strengthen the anti-infective treatment, firstly empirical medication, anti-inflammatory treatment with antibiotics, pending the return of the results of bacterial culture or to adjust the use of antibiotics according to the results of the culture of the secretion and the results of drug sensitivity test; 3, the patient needs to eat high-protein, high-calorie, high vitamin food, in order to enhance the body’s resistance, and to promote the healing of the wound.