Nitric oxide poisoning is relatively common in industry, inhaling a large amount of nitric oxide in a short period of time, the clinical manifestations of respiratory damage and chest X-ray signs, combined with blood gas analysis and on-site labor hygiene investigation data, can be analyzed comprehensively to consider this disease. The principle of treatment is to quickly get out of the scene of poisoning, lying down, keeping warm, avoiding activities, immediately inhaling oxygen, and giving symptomatic treatment. Those who react to irritation should be observed for 1-3 days, and during the observation period, activities should be strictly limited, bed rest, keep quiet, keep the respiratory tract open, and if possible, give nebulized inhalation to relieve bronchial spasm, and perform tracheotomy if necessary. Early, adequate amount, short-term use of glucocorticoid therapy, reasonable oxygen therapy, in order to solve the problem of nitric oxide poisoning.