The headache may be caused by low cranial pressure syndrome, cervical spondylosis and other diseases. 1. Low Cranial Pressure Syndrome: headache lying down without pain on pain may be suffering from low cranial pressure syndrome, due to the headache caused by the reduction of intracranial pressure when you get up, you can intravenous large amount of saline supplementation in order to relieve the symptoms of low cranial pressure syndrome. 2. Cervical spondylosis: headache lying down does not hurt when you get up may also be caused by cervical spondylosis, prominent cervical vertebrae compression of the surrounding blood vessels, resulting in a reduction in the amount of blood circulating in the brain, stand up after the neck muscle tension, will aggravate the pressure on blood vessels, resulting in cerebral ischemia, the emergence of the symptoms of headache, lying down when the neck relaxation, the symptomatic relief, the cervical vertebrae anterior discectomy interlaminar fusion surgery treatment. Patients who have headaches lying down without pain and get up with pain are recommended to go to the hospital in time, after clarifying the cause of the disease, according to the doctor’s guidance for standardized treatment.