Transverse furrow spinning visible in the fingernails is a typical symptom of cutaneous mucosal lymph node syndrome, also known as Kawasaki disease, an acute febrile rash pediatric disease with systemic vasculitis as the main lesion. It is currently considered to be an immune-mediated vasculitis, with a predilection for the coronary arteries of the heart. So how is Kawasaki disease examined clinically? 1. Peripheral blood WBC is increased, predominantly neutrophils, with leftward nuclear shift. Platelets are normal in the early stage and increase in the 2nd-3rd week, which can assist in the diagnosis. increased ESR, CRP and other acute phase proteins, plasma fibrinogen and plasma viscosity are elevated in those with elevated serum transaminases. 2.Serum IgG, IgM, IgA, IgE and circulating immune complexes are elevated. TH2-like cytokines such as IL-6 are significantly increased, and total complement and C3 are normal or increased. 3.Electrocardiogram: early stage shows non-specific ST-T changes; in pericarditis, there may be extensive ST-segment elevation and low voltage; in myocardial infarction, there is significant ST-segment elevation, T-wave inversion and abnormal Q waves. 4.Chest plain film: It may show increased lung texture, blurred or lamellar shadow, and heart shadow may be enlarged. 5.Echocardiography: pericardial effusion, coronary artery inner diameter dilatation, coronary artery aneurysm and coronary artery stenosis can be seen in the acute stage. It is the safest and accurate method to diagnose Kawasaki disease complicated by coronary artery lesions.