Many people know that Parkinson’s disease is mostly found in the elderly population, but in recent years, the trend of onset is getting younger and younger, with a gradual increase in patients in their 40s and 50s. When Parkinson’s patients show more obvious symptoms such as hand tremors, the dopamine in the brain has been affected, so Parkinson’s disease must be detected and treated early. For the precursors of Parkinson’s disease, the professor made the following points: 1. Is there tremor in the arms or other parts of the body? Although there are many diseases that cause tremor, the tremor in Parkinson’s disease is “not trembling when moving, but appearing at rest and intensifying when nervous”. Later on, the tremor only appears when the limb is at rest, and is reduced or stopped when changing position or movement, so it is called resting tremor. The tremor increases when the patient is excited or nervous, and can disappear completely during sleep. 2.Do you find that your sense of smell is diminished and constipation occurs? Decreased sense of smell and constipation are the most alert and important warning signs of Parkinson’s disease in medical science today. You may feel that you are not as sensitive to some smells as before, even the smell of durian, sauerkraut or kimchi is not detectable, and your original bowel habits are also affected, it is time to see a doctor. 3.Do you find yourself having difficulty walking? When you move around, your body is stiff and does not listen to you, and that stiffness still exists after you try to move around. Some people even say, “Why do you look like a robot when you walk? 4. Is there any delay in movement or small writing? The movements of putting on clothes, buttons, shoelaces, shoes, etc. are much slower than before, or cannot be completed smoothly; writing gradually becomes difficult, the handwriting is bent, and the font is getting smaller and smaller. When dyskinesia is manifested in the face, facial muscle movement is reduced, as if wearing a false mask, with dull expression, reduced blinking, and frequent double-eyed staring in front. 6.Is there a speech disorder? The specific manifestations are: unclear speech, flat tone of speech, no intonation, monotonous rhythm, etc. 7.Is there any sleep disorder? Seventy percent of Parkinson’s patients have various sleep disorders. These include: excessive daytime sleepiness, fist-pumping, shouting and nightmares at night. 8.Is there a tendency of depression? About 40-55% of Parkinson’s patients will experience depression, which is manifested by symptoms such as easy fatigue, loss of appetite, loss of interest, lack of self-confidence, and emotional instability. Depression can occur at any stage of Parkinson’s disease. The early stage of Parkinson’s is the peak of depression, so catch the early signal and prevent it as early as possible.