Parkinson’s disease in addition to drug treatment, there are surgical treatment methods, let’s learn together: a. What are the surgical methods 1. destruction: due to serious adverse reactions, in developed countries has been largely no longer used this approach. 2. DBS surgery (deep brain electrical stimulation therapy): currently the best surgical treatment for Parkinson’s. 3. Stem cell transplantation: It is still in the experimental stage, and the efficacy is not yet clear. What is DBS surgery (deep brain electrical stimulation therapy)? Deep brain electrical stimulation therapy uses electrodes implanted in the brain to send electrical stimulation to suppress abnormal brain nerve signals. The stimulation is delivered to precise targets related to motor control. This therapy allows Parkinson’s patients to normalize motor function, reduce symptoms and improve quality of life. Third, how effective is DBS in treating Parkinson’s disease Clinical studies have shown that DBS has significant therapeutic effects in treating Parkinson’s disease: (1) it can improve patients’ symptoms such as tremor, rigidity, slow or inability to move, and balance disorders; (2) it reduces the dose of oral medication; and (3) it can significantly improve patients’ quality of daily life and ability. Experience shows that the effect is significant in patients who respond well to levodopa. 4. What kind of patients are suitable for DBS surgery 1. Patients who are clearly diagnosed with primary Parkinson’s disease 2. Patients who used to have good efficacy on levodopa, but now the efficacy of the drug has gradually decreased or side effects have appeared, and the disease has begun to affect normal work and life 3. Patients who have no obvious intellectual impairment and are willing and able to cooperate during the surgery and subsequent follow-up 5. Contraindications and risks of DBS surgery DBS is a kind of surgery, so all patients with contraindications to surgery are not suitable for the surgery, DBS has certain surgical complications like other brain surgeries, but as long as the surgical indications are selected appropriately, the incidence of surgical complications is low. Follow-up after DBS Since Parkinson’s is a progressive disease, it is very important to follow up after DBS implantation by adjusting the stimulation frequency, pulse width and voltage to achieve the best disease control and the least side effects. Follow-up visits are conducted 1-3 times a year for modulation testing.