Waking up in the morning with a dry mouth and bitter mouth may be caused by environmental factors, sleep habits, but also may be caused by diabetes and digestive diseases and other factors, according to different causes to take to improve the environment, medication, surgical treatment and other methods. 1. Environmental factors: long-term in a dry environment, or not timely replenishment of water, will also appear in the waking up of dry mouth and bitter mouth. It is recommended to replenish water and moisten the air in time. 2. Sleeping habits: Some people unconsciously open their mouths to breathe when they sleep, such as snoring. The inhaled air is not moisturized by the nasal cavity, and it is easy to have a bitter and dry mouth in the morning. It is recommended to adjust the sleeping position, and for those who snore seriously, you can go to the ENT department to see if there is adenoid hypertrophy and other causes, and if necessary, surgical treatment. 3. Diabetes: mainly because of the body’s insulin secretion is insufficient, so that the blood glucose concentration in the blood, resulting in high osmotic pressure in the blood, urine discharge increased, causing dry mouth, thirst and other symptoms. It is recommended to go to the hospital in time to take blood test, observe the change of blood glucose, and adjust the medication under the doctor’s guidance, such as adjusting the amount of insulin injection. 4. Gastrointestinal diseases such as bile reflux, etc.: It is recommended to take acid-suppressing drugs such as omeprazole, gastric mucosal protectants such as colloidal bismuth pectin, and gastrointestinal stimulants such as itopride under the guidance of a doctor. Prolonged non-relief and aggravation of symptoms, it is recommended to go to the hospital in time to identify the causes and targeted treatment.