Kidney problems in women are manifested by edema, cardiac insufficiency, anemia, acid-base balance imbalance and internal environment disorders. Kidney has the function of excreting metabolic wastes, regulating acid-base balance and endocrine, etc. The so-called “bad kidney” usually involves the above aspects. When a woman’s kidney is not good, depending on the degree of the lesion, it can have excretory dysfunction, resulting in sodium retention and edema. In severe cases, volume overload occurs, leading to cardiac insufficiency, chest tightness and shortness of breath. In patients with chronic renal insufficiency, erythropoietin secretion is insufficient, and renal anemia can occur. Laboratory tests of renal function will show high blood creatinine and increased urea nitrogen, anemia, hyperkalemia, hyperphosphatemia, etc. Female patients will have fatigue and poor appetite, loss of appetite, nausea and vomiting. There can also be acid-base balance imbalance, internal environment disorder, metabolic acidosis, hyperkalemia, etc., which is manifested as malaise, palpitation (rapid heartbeat, often accompanied by panic) and other discomforts. To sum up, according to the severity and duration of kidney disease, the manifestations of female kidney disease are diversified and need to be analyzed on a case-by-case basis. It is recommended that female patients with kidney disease should go to regular hospitals in time and receive standardized treatment under the guidance of physicians.