Closed mouth is closed mouth pimples, a kind of acne, although belongs to the mild acne, but there is no simple way to remove, mainly standardized treatment and life regulation. 1. Standardized treatment: apply adapalene gel, all-trans retinoic acid cream and other drugs to relieve, when the effect is not good, you can choose to dissolve the role of acne benzoyl peroxide, azelaic acid. You can also perform acne removal under sterile conditions, using an acne squeezer to squeeze out the acne. 2. Life regulation: the formation of closed mouth and lifestyle also has a great relationship, should pay attention to, usually do not eat too much greasy food, regular work and rest, go to bed early and get up early, to avoid too much mental stress, usually go outdoors to do sports, keep the skin clean and hygienic, and choose the right skincare products. Each person’s physical condition is different, the severity of the disease is different, the treatment may vary, it is recommended that under the guidance of the doctor to standardize the treatment, the above drugs should be used in accordance with medical advice.