Warfarin anticoagulation guidelines

This article is for scientific use only and is not responsible for any results resulting from self-adjustment of the dose. International Normalized Ratio (INR value) Warfarin dose adjustment 1.0-1.2 25% increase in weekly dose i.e. from 1 tablet per day to 1.25 tablets per day 1.2-1.5 10-15% increase in weekly dose i.e. from 1 tablet per day to 1 tablet per day 1.25 tablets per day alternating 1.5-1.8 5-10% increase in weekly dose i.e. from 1 tablet per day to 1 tablet per day for two days 1.25 tablets per day 1.25 tablets alternately for a three-day cycle 1.8-2.5 Unchanged 2.5-3.0 Weekly dose reduction of 5-10% i.e. from 1 tablet a day for two days to 1 tablet a day alternately to 1 tablet a day 3.0-3.9 Weekly dose reduction of 10-20% i.e. from 1 tablet a day to 1 tablet a day alternately to 1 tablet a day 4.0-5.0 Vitamin K1 against, weekly dose reduction of 25% i.e. from 1 tablet a day to 1 tablet a day alternately Dose reduced by 25% from 1.25 tablets per day to 1 tablet per day