The soles of the feet were bitten by mosquitoes, can be used externally to stop itching, glucocorticoids, if necessary, with oral antihistamine, antibiotic drugs treatment. 1. Stop itching: the soles of the feet by mosquito bites, may cause obvious itching sensation, is a kind of allergic reaction. Topical antipruritic ointments, such as compound Benadryl cream and compound chlorpheniramine maleate tincture, can be given to help relieve itching. 2. Glucocorticosteroids: Glucocorticosteroids, such as hydrocortisone butyrate and tretinoin cream, have anti-inflammatory and anti-allergic effects. 3. Antihistamine: If the itching symptoms are more obvious, systemic systemic medication can be given antihistamines, such as loratadine, cetirizine hydrochloride, orotidine hydrochloride, etc., which have good anti-itching and anti-allergic effects. 4. Antibiotics: If scratching induces bacterial infection, antibiotics can be given when necessary, such as erythromycin, amoxicillin and so on. Mosquito bites can cause itching, it is recommended to avoid scratching, irritation, induced infection. If the symptoms are obvious, it is recommended to go to the dermatology department of the hospital, combined with the doctor’s advice to give the appropriate drug treatment.