Thighs appear difficult, indescribable kind of feeling, may be a muscle problem, may also be the problem of nerve sensory abnormalities: 1, if it is a muscle problem, usually are muscle strain or muscle chronic inflammation caused by. It is common in people who do strenuous lower limb exercises for a long time, such as running, jumping, playing soccer, basketball and other sports, the muscles of the thighs are prone to chronic inflammation caused by strain. Generally there is not much symptom during the daytime activities, but the symptom is more obvious after standing still or not moving at night.2. Neurological symptoms, commonly lumbar intervertebral disc herniation, lumbar spinal stenosis or lumbar triple transverse syndrome, may affect the nerves of the thighs, which may lead to the abnormal sensation of the nerves of the thighs, and symptoms such as numbness, fatigue, and tugging pain may appear.