There are many causes of pain in the buttocks and thighs when walking, and the common causes are as follows: lumbar disc herniation, pear-shaped muscle syndrome, sciatic nodal bursitis, and large femoral nodal bursitis, etc. All of the above diseases can lead to painful symptoms in the buttocks and thighs when walking. If these symptoms occur, avoid strenuous activities, pay attention to rest, and take oral anti-inflammatory and analgesic treatment with non-steroidal anti-inflammatory drugs. For example, you can take diclofenac sodium extended-release tablets and ibuprofen capsules, etc. You can also take some oral Chinese medicine to activate blood circulation and remove blood stasis, and you can also cooperate with acupuncture, physiotherapy and massage, which also have very good effect. If the symptoms are not significantly relieved after the above treatment, you need to go to the hospital in time to improve the relevant examination, to clarify the cause and treat the disease.