Vascular pain in the head, mostly caused by the dilation of blood vessels, is seen in patients with high blood pressure. If blood pressure is too high it may cause vasodilatation in the brain and the patient may develop headache. In severe cases, hypertensive encephalopathy may also occur and the patient may experience nausea, vomiting, and may also become unconscious, etc. It should be treated by actively regulating blood pressure. It may also be a primary headache disease, such as migraine and cluster headache, both of which are a primary neurovascular headache. In migraine patients, the main manifestation is recurrent one-sided throbbing headache, while nausea and vomiting can occur, which is mainly treated symptomatically. Oral ibuprofen, indomethacin and naproxen can be given in mild cases, and ergotamine caffeine and zolmitriptan can be applied in severe cases. In cluster headache, the headache is usually more intense in patients, mostly stabbing, pulling and tearing pain. The headache is usually located in the periorbital area of one eye, but there may also be a frontal or temporal headache on one side, which may be accompanied by conjunctival hemorrhage, nasal congestion and tearing. Most patients have nocturnal onset and are treated mainly with zolmitriptan, or sumatriptan.