24h urine protein quantitative 3179mg, mainly seen in diabetic nephropathy, hypertensive nephropathy and glomerulonephritis, etc., can be prescribed oral dagliflozin, valsartan, Benadryl, prednisone acetate, cyclosporine and other drugs treatment. 1. Diabetic nephropathy: the endothelial cells between the glomerulus and tubules of such patients increase in size, which leads to leakage of urinary proteins, which can be reduced by oral dagliflozin, valsartan, tretinoin and other drugs to slow down the process of the disease. 2. Hypertensive nephropathy: Hypertension can increase the permeability of the glomerular basement membrane, resulting in large molecules of protein filtered out of the original urine, thus appearing in the urine protein. It can be effectively controlled by renin-angiotensin-aldosterone receptor antagonists (such as captopril tablets, benadryl, valsartan, etc.), which can also reduce urinary protein. 3. Glomerulonephritis: It is mainly due to the damage of molecular barrier and charge barrier of glomerular filtration membrane, which leads to the appearance of urinary protein. You can improve the renal puncture biopsy, clear pathology type, follow the doctor’s instructions oral prednisone acetate, cyclosporine and other drugs treatment. All of the above drugs should be used under the guidance of a physician, and should not be used without authorization, so as not to delay the condition. The high urine protein, it is recommended to timely regular hospitals, identify the cause of the disease, with the doctor for targeted treatment.