24 hours urine protein 2000mg is more serious. The presence of urine protein not only suggests that you may have nephritis, but urine protein can also cause damage to the kidneys, leading to gradual worsening of kidney function and even the development of uremia, so it is more serious. The increase in urine protein needs to be clarified as to what type of nephritis it is, whether chronic nephritis, acute nephritis or secondary nephritis, such as purpura nephritis, hepatitis B virus-associated nephritis, etc., and then be treated according to the cause. You can also use some drugs to lower urine protein, such as Irbesartan, Perindopril and so on. Some Chinese medicines are also effective in lowering urine protein, such as Huangkui capsules, which can also be applied. Sometimes you have to use hormones and immunosuppressants to treat together, both of which are more effective in lowering urine protein, but have more side effects. Try to reduce the 24-hour urine protein quantification to below 500mg so that the damage to the kidneys can be minimized.