Interventional therapy can improve the chance of surgery when stage III liver cancer is inoperable. Stage III liver cancer belongs to intermediate and advanced liver cancer, and the cancer cells are prone to metastasis and spreading, which makes surgical treatment more difficult. Interventional therapy is an important clinical treatment for liver cancer, which mainly includes selective hepatic artery chemoembolization, etc. It can reduce the size of tumor lesions, and has the features of significant near-term curative effect, less complication, less damage and easy to repeat. Interventional therapy can reduce the tumor stage, and the obvious shrinkage of tumor can provide opportunities for surgical treatment, but doctors need to evaluate the condition, including the size of tumor volume, the number of cancer cells, the invasion of vasculature and so on, and surgical treatment can be considered if it meets the conditions for surgery. When liver cancer is in middle or late stage, standardized treatment should be carried out under the guidance of doctors in order to alleviate the condition and improve the quality of life.