Pituitary disorders may have a little bit to do with large bone age, but they can also be due to other causes such as diet and hyperthyroidism. The pituitary gland secretes growth hormone, and abnormalities in the function of this secretion can lead to large bone age. In addition, large bone age and precocious puberty have a certain relationship, pituitary tumors are also an important cause of precocious puberty, pituitary tumors lead to hypothalamus pituitary gonadal axis dysfunction caused by precocious puberty, the child may appear large bone age. If the child is given foods containing large amounts of sex hormones for a long period of time, it can also lead to large bone age. Large bone age may also be caused by other diseases, such as hyperthyroidism, adrenocortical hyperplasia, etc., which should be examined in time and treated symptomatically. For patients with large bone age, timely treatment should be carried out.