Long-term alcoholism in men may lead to alcoholic cirrhosis, gastritis, gout and other diseases. 1. Alcoholic cirrhosis of the liver: after alcohol enters the human body, except for a small amount discharged through the digestive tract, the vast majority of alcohol is metabolized in the liver, and ethanol and other components of alcohol can directly damage the liver cells, causing fatty degeneration and necrosis of the liver cells, and in the long run, leading to cirrhosis of the liver. 2. Gastritis: Because alcohol stimulates the gastric mucosa, it may cause mucosal damage, thus gastritis. Serious patients may also develop gastric ulcer, gastric perforation and other diseases. 3. Gout: Because wine contains a lot of purine, due to long-term alcoholism can cause the body purine metabolism disorders, thus appearing gout. Long-term alcohol abuse of men in addition to the above diseases, there are other diseases, it is recommended to quit drinking as soon as possible or minimize the consumption of alcohol.