Nursing diagnosis and management of pituitary tumors focuses on the aftermath of surgery. Before the surgery, the main preparation for the surgery includes picking out the nose hairs one day before the surgery, cough reflex and bowel training before the surgery, and so on. After the surgery, the care is more important: first, we must pay attention to sleep, sleep is a very important thing, if the patient has insomnia, need to inform the doctor in time for appropriate medication. Second, we must control the stability of vital signs, especially for blood pressure, to reduce postoperative bleeding again. Third, insist on coughing and corresponding deep breathing exercise, reduce the occurrence of lung infection. Fourth, we must strengthen the turn over and pat the back, early down activities to reduce the lower extremity venous thrombosis decubitus ulcer formation probability. Fifth, the diet must be based on a liquid diet to reduce gastrointestinal discomfort, such as gas defecation is changed to a semi-liquid diet, and gradually restore the function of the gastrointestinal tract.